ea0015p291 | Reproduction | SFEBES2008
Dennedy Michael
, Noctor Eoin
, McKenna T Joseph
, O'Shea Donal
Raised body mass index (BMI) is seen in 95% of PCOS patients, which is characterised by hyperandrogenaemia, both clinically and biochemically. Weight loss, using calorie restricted diets, have previously been successful in improving androgen profiles and also restoring fertility in obese PCOS patients. A CB1 cannabinoid receptor antagonist, rimonabant is effective in achieving weight loss in subjects with a BMI >27 kg/m.This study aimed to...